The OR2M2 Antibody (PACO4213) is a polyclonal antibody specifically designed for research involving the OR2M2 protein, a member of the human olfactory receptor family. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.OR2M2, a G protein-coupled receptor, plays a crucial role in olfactory signal transduction, specifically in the detection of odorants. Its expression in olfactory sensory neurons enables the detection and discrimination of a wide range of odorous molecules, contributing to our sense of smell.
Research into OR2M2 is essential for understanding the mechanisms underlying olfaction and sensory perception.Moreover, the potential implications of OR2M2 in various diseases and conditions, such as anosmia (loss of sense of smell) and neurodegenerative disorders, make it an interesting target for further investigation. By studying the function and regulation of OR2M2, researchers can gain insights into olfactory physiology and pathophysiology, paving the way for potential therapeutic developments in related fields.
Antibody Name:
OR2M2 Antibody
Antibody SKU:
PACO04213
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 2M2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
OR2M2; Olfactory receptor 2M2; OST423
UniProt Protein Function:
Odorant receptor.
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]