The OR2L13 Polyclonal Antibody (PAC038238) is a valuable tool for researchers studying OR2L13, a member of the odorant receptor (OR) family involved in olfaction. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding specifically to the OR2L13 protein, this antibody enables the detection and analysis of OR2L13 in a variety of cell types, making it ideal for studies in sensory biology and neuroscience research.
OR2L13 is a key player in the olfactory system, playing a crucial role in detecting and responding to specific odors. Research into OR2L13 function can provide insights into how the brain processes olfactory information and how sensory stimuli influence behavior. By understanding the role of OR2L13, researchers can gain a better understanding of the mechanisms underlying olfaction and potentially develop new strategies for treating olfactory disorders or enhancing sensory perception.
Western blot. All lanes: OR2L13 antibody at 6µg/ml + Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa.
Immunofluorescent analysis of HepG2 cells using PACO38238 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
OR2L13: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1Chromosomal Location of Human Ortholog: 1q44Cellular Component: integral to membrane; plasma membraneMolecular Function: olfactory receptor activity; protein bindingBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
