The OR2D2 Antibody (PACO3415) is a high-quality polyclonal antibody designed for research involving the olfactory receptor OR2D2. This antibody, raised in rabbits, is highly specific and reactive with human samples. It has been validated for use in various applications, including Western blot, immunohistochemistry, and flow cytometry, allowing for versatile and comprehensive analysis of OR2D2 expression.Olfactory receptor OR2D2 is a cell surface receptor primarily found in the olfactory epithelium, where it plays a crucial role in detecting specific odor molecules. Research on OR2D2 is important for understanding the mechanisms of olfactory perception and how it influences behavior and physiology.
Additionally, dysregulation of OR2D2 has been implicated in certain olfactory disorders and neurodegenerative diseases, making it a potential target for therapeutic interventions.This antibody provides researchers with a valuable tool for studying the expression, localization, and function of OR2D2 in various biological contexts. By elucidating the role of OR2D2 in olfaction and its potential involvement in disease processes, this antibody contributes to advancing our understanding of sensory perception and developing new therapeutic strategies for olfactory-related conditions.
Antibody Name:
OR2D2 Antibody
Antibody SKU:
PACO03415
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 2D2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2D2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCRChromosomal Location of Human Ortholog: 11p15.4Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
