The OR2AT4 Antibody (PAC004104) is a polyclonal antibody designed for research involving OR2AT4, a G protein-coupled receptor that plays a critical role in olfactory signaling. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications such as immunohistochemistry and flow cytometry. It binds specifically to the OR2AT4 protein, enabling detection and analysis in different cell types, making it ideal for studies in neuroscience and sensory research.OR2AT4 is known for its involvement in the perception of specific odorants, making it a fascinating target for investigating olfactory processes and sensory perception. Understanding the function and regulation of OR2AT4 can provide valuable insights into how the olfactory system works and how it contributes to our sense of smell.
Research on OR2AT4 could have implications for areas such as fragrance development, pheromone signaling, and neurological disorders related to olfactory dysfunction.Overall, the OR2AT4 Antibody is a valuable tool for researchers interested in unraveling the mysteries of olfactory signaling and exploring the complex interactions between odorant receptors and the brain. Its specificity and sensitivity make it a reliable choice for studies seeking to uncover the role of OR2AT4 in human physiology and the impact of olfaction on various aspects of health and behavior.
Antibody Name:
OR2AT4 Antibody
Antibody SKU:
PACO04104
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 2AT4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2AT4: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 11q13.4Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
