The OR2AG2/OR2AG1 Polyclonal Antibody (PACO02487) is a valuable tool for researchers studying olfactory receptor proteins. These proteins play a crucial role in the detection and discrimination of odor molecules, making them essential for understanding the sense of smell. The antibody, produced in rabbits, is highly specific to the OR2AG2 and OR2AG1 proteins in humans and is validated for use in various research applications, including immunohistochemistry and flow cytometry.OR2AG2 and OR2AG1 are members of the olfactory receptor family, which are G protein-coupled receptors expressed in the olfactory sensory neurons of the nasal epithelium. By binding to specific odor molecules, these receptors initiate a signal transduction pathway that ultimately leads to the perception of smell.
Research on olfactory receptors is important for unraveling the mechanisms of odor detection and sensory processing in the brain.Studying OR2AG2 and OR2AG1 can provide insights into the molecular basis of olfaction and how different odor molecules are detected and distinguished by the olfactory system. This knowledge can have applications in diverse fields such as food industry, fragrance development, and neurobiology. The OR2AG2/OR2AG1 Polyclonal Antibody is a valuable tool for advancing our understanding of olfactory receptor proteins and their role in the sense of smell.
Antibody Name:
OR2AG2/OR2AG1 Antibody
Antibody SKU:
PACO02487
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 2AG1/2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2AG2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 11p15.4Cellular Component: integral to membrane; plasma membraneMolecular Function: olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
