The OR2AE1 Antibody (PACO05415) is a highly specific and sensitive tool for research involving the OR2AE1 protein, a member of the olfactory receptor family. The antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including immunohistochemistry and flow cytometry. By binding to the OR2AE1 protein, this antibody allows for the detection and analysis of OR2AE1 expression in different cell types, making it perfect for studies in olfaction and sensory perception.
OR2AE1, also known as olfactory receptor family 2 subfamily AE member 1, is involved in the detection of specific odors and plays a crucial role in the sense of smell. Research into OR2AE1 can provide insights into how the olfactory system functions and how it contributes to behaviors such as food preference and mate selection. By studying OR2AE1, researchers can better understand olfactory processing and potentially develop new approaches for manipulating smell perception in various contexts.
Antibody Name:
OR2AE1 Antibody (PACO05415)
Antibody SKU:
PACO05415
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:10000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human Olfactory receptor 2AE1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2AE1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 7q22.1Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
