The OR2A14/OR2A5 Antibody (PACO03475) is a reliable tool for studying the olfactory receptors OR2A14 and OR2A5, which are involved in odor recognition and perception. This polyclonal antibody is raised in rabbits and has been validated for use in various research applications, including immunofluorescence and flow cytometry. It specifically binds to the OR2A14 and OR2A5 proteins, allowing for their detection and analysis in different cell types and tissues.These olfactory receptors play a crucial role in the sense of smell and are essential for recognizing and responding to various odors in the environment.
Studying the function and regulation of OR2A14 and OR2A5 can provide valuable insights into olfactory perception and potentially lead to the development of new therapeutics for conditions related to smell and taste disorders.Overall, the OR2A14/OR2A5 Antibody (PACO03475) is a valuable tool for researchers interested in understanding the molecular mechanisms underlying olfactory perception and exploring the potential therapeutic implications of targeting these receptors. Its high specificity and sensitivity make it an ideal choice for studies in neuroscience, sensory biology, and related fields.
Antibody Name:
OR2A14/OR2A5 Antibody
Antibody SKU:
PACO03475
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 2A5/14.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2A14: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 7q35Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
