The OR2A1 Polyclonal Antibody (PACO02837) is a valuable tool for researchers studying olfactory receptor 2A1, a protein involved in odor detection and olfactory signal transduction. This antibody, produced in rabbits, has been extensively validated for use in various research applications, particularly in Western blotting.Olfactory receptor 2A1 is a G protein-coupled receptor found in the olfactory sensory neurons of the nasal cavity. It plays a critical role in the detection and discrimination of different odors, contributing to our sense of smell.
Research on OR2A1 is important for understanding the molecular mechanisms underlying olfaction and how our brains perceive and interpret different scents.By using the OR2A1 Polyclonal Antibody, researchers can accurately detect and analyze the expression of OR2A1 in different cell types and tissues, advancing our knowledge of olfactory receptor function. This antibody is a valuable tool for studies in the fields of neuroscience, sensory biology, and odor perception.
Antibody Name:
OR2A1; Antibody
Antibody SKU:
PACO02837
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 2A42.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2A1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1Chromosomal Location of Human Ortholog: 7q35Cellular Component: integral to membrane; plasma membraneMolecular Function: olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]