The OR1S2/OR1S1 Polyclonal Antibody (PACO06710) is specifically designed for research involving the OR1S2 and OR1S1 proteins, which are members of the olfactory receptor family. These proteins play a crucial role in the detection and discrimination of odor molecules, making them essential for understanding the mechanisms of olfaction.Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in various applications, including Western blotting. By binding to the OR1S2 and OR1S1 proteins, this antibody enables the detection and analysis of these proteins in different cell types, providing invaluable insights into olfactory processes.
Given the importance of olfactory receptors in various physiological and pathological processes, such as sensory perception and neurological disorders, the OR1S2/OR1S1 Polyclonal Antibody is an indispensable tool for researchers in the fields of neuroscience, pharmacology, and sensory biology. Its ability to accurately detect and quantify OR1S2 and OR1S1 proteins makes it a valuable asset for studies aiming to unravel the complexities of olfactory signaling pathways and their implications in health and disease.
Antibody Name:
OR1S2/OR1S1 Antibody (PACO06710)
Antibody SKU:
PACO06710
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:20000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human Olfactory receptor 1S1/2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of various cells using Olfactory receptor 1S1/2 Polyclonal Antibody.
Western Blot analysis of HuvEc cells using Olfactory receptor 1S1/2 Polyclonal Antibody.
OR1S2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1Chromosomal Location of Human Ortholog: 11q12.1Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; transmembrane receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
