The OR1K1 Polyclonal Antibody (PAC064371) is a valuable tool for researchers studying OR1K1, a member of the olfactory receptor family, involved in odorant detection and signal transduction. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the OR1K1 protein, enabling precise detection and analysis in a variety of cell types, making it an ideal choice for studies in neuroscience and sensory research.
OR1K1 plays a crucial role in olfactory sensation, detecting specific odorant molecules and transmitting signals to the brain for interpretation. Understanding the function of OR1K1 is essential for unraveling the complexities of the olfactory system and its impact on behavior and perception. Researchers investigating olfaction, taste perception, and sensory processing will benefit from using this antibody to explore the role of OR1K1 in these processes.
Antibody Name:
OR1K1 Antibody (PACO64371)
Antibody SKU:
PACO64371
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:1000-1:5000, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 1K1 protein (261-273AA)
Western Blot. Positive WB detected in: A549 whole cell lysate. All lanes: OR1K1 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 35 kDa. Observed band size: 35 kDa.
Immunofluorescence staining of Hela cells with PACO64371 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Odorant receptor.
Synonyms:
Olfactory receptor 1K1, OR1K1
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
