The OR1D2 Polyclonal Antibody (PAC028734) is a powerful tool for researchers studying the OR1D2 protein, a member of the olfactory receptor family involved in detecting odors. This antibody, generated in rabbits, has high specificity for human samples and is validated for use in applications such as immunofluorescence and flow cytometry. By binding to OR1D2, this antibody allows for accurate detection and analysis of the protein in various cell types, making it ideal for studies in olfactory research and sensory biology.
OR1D2 is essential for olfaction, playing a key role in detecting specific odors and triggering neural responses. Understanding the function and regulation of OR1D2 is crucial for unraveling the complex mechanisms of smell perception and sensory processing. Research on OR1D2 can provide valuable insights into neurological disorders related to olfactory dysfunction and contribute to the development of novel therapies targeting olfactory receptors.
Antibody Name:
OR1D2 Antibody (PACO28734)
Antibody SKU:
PACO28734
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Olfactory receptor 1D2 protein (159-196AA)
Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception.
OR1D2: Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 17p13.3Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: olfactory receptor activityBiological Process: cell motility; G-protein coupled receptor protein signaling pathway; protein import into nucleus, translocation; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
