The OR1D2 Polyclonal Antibody (PACO04484) is a valuable tool for researchers studying OR1D2, a member of the olfactory receptor family involved in detecting odors. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various experimental applications, including Western blotting.OR1D2 is a key player in the olfactory system, contributing to our sense of smell by detecting specific odor molecules. By targeting OR1D2 with this antibody, researchers can gain insights into the mechanisms underlying olfaction and how different odorants are perceived and processed by the brain.
The OR1D2 Polyclonal Antibody is a crucial resource for studies in sensory biology, neurobiology, and related fields. Its high specificity and reliability make it an essential tool for unraveling the complexities of the olfactory system and understanding how we perceive the world through our sense of smell.
Antibody Name:
OR1D2 Antibody
Antibody SKU:
PACO04484
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 1D2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR1D2: Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 17p13.3Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: olfactory receptor activityBiological Process: cell motility; G-protein coupled receptor protein signaling pathway; protein import into nucleus, translocation; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
