The OR12D3 Polyclonal Antibody (PACO05430) is a valuable tool for researchers studying the OR12D3 protein, a member of the olfactory receptor family involved in the detection of specific odor molecules. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.OR12D3 plays a crucial role in the olfactory system, recognizing and transmitting signals related to specific odors to the brain. Understanding the function of OR12D3 can provide insights into how the sense of smell works and how it impacts behavior and physiology.
Research on olfactory receptors like OR12D3 has implications for various fields, including neuroscience, sensory biology, and even the development of new fragrance products.By using the OR12D3 Polyclonal Antibody, researchers can accurately detect and analyze the OR12D3 protein in different cell types and tissues, facilitating investigations into the molecular mechanisms underlying olfactory perception. This antibody is an essential tool for advancing our understanding of how the sense of smell influences human health and behavior.
Antibody Name:
OR12D3 Antibody (PACO05430)
Antibody SKU:
PACO05430
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human Olfactory receptor 12D3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR12D3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCRChromosomal Location of Human Ortholog: 6p22.1Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
