The OR10K1/OR10K2 Antibody (PACO04210) is a polyclonal antibody designed for research involving OR10K1/OR10K2, olfactory receptors that play a role in the detection of odorants. This antibody, raised in rabbits, is highly reactive with human and rat samples and is validated for use in various applications including Western blot and immunohistochemistry. OR10K1/OR10K2 are members of the olfactory receptor family, which are G protein-coupled receptors involved in the detection of odor molecules. These receptors play a crucial role in the sense of smell and are important for communication, navigation, and survival in many species.
Research into olfactory receptors like OR10K1/OR10K2 has implications in multiple fields including neuroscience, sensory biology, and even cancer research, where olfactory receptors have been found to play a role in tumor growth and progression. Understanding the function and regulation of OR10K1/OR10K2 can provide valuable insights into olfaction, as well as potential therapeutic targets in various diseases and conditions.
Antibody Name:
OR10K1/OR10K2 Antibody
Antibody SKU:
PACO04210
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 10K1/2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
