The OR10K1 Polyclonal Antibody (PACO64359) is specifically designed for research involving OR10K1, a member of the olfactory receptor (OR) gene family. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in a variety of applications, including Western blotting. By binding to the OR10K1 protein, this antibody allows for the detection and analysis of OR10K1 expression in different cell types, making it an excellent tool for studying olfactory receptor function and related processes.The OR10K1 gene encodes a protein that is involved in the detection of distinct odorants, playing a crucial role in the sense of smell.
Understanding the function and regulation of OR10K1 can provide valuable insights into olfactory perception and its impact on behaviors and physiological processes. Research on OR10K1 may also contribute to the development of novel strategies for diagnosing and treating conditions related to olfactory dysfunction. By utilizing the OR10K1 Polyclonal Antibody, researchers can further explore the complexities of olfactory receptor signaling and its implications in health and disease.
Antibody Name:
OR10K1 Antibody (PACO64359)
Antibody SKU:
PACO64359
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 10K1 protein (259-272AA)
Immunofluorescence staining of SH-SY5Y cells with PACO64359 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
