The OR10A7 Monoclonal Antibody (PAC00251) is a powerful tool for researchers studying OR10A7, a member of the olfactory receptor family involved in detecting specific odorants. This antibody, produced in mice, shows high specificity for human samples and has been validated for use in immunohistochemistry applications. It binds specifically to the OR10A7 protein, allowing for precise detection and localization in various tissues and cell types.OR10A7, also known as olfactory receptor 10A7, plays a crucial role in the sense of smell by recognizing specific odor molecules and transmitting this information to the brain.
Understanding the function and expression pattern of OR10A7 can provide valuable insights into olfactory perception and its role in disease states such as anosmia (loss of smell). This antibody is a valuable tool for researchers investigating the olfactory system and its implications in health and disease.
Antibody Name:
OR10A7 Antibody
Antibody SKU:
PACO02451
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 10A7.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR10A7: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCRChromosomal Location of Human Ortholog: 12q13.2Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
