The OR10A2 Polyclonal Antibody (PAC064355) is a key tool for researchers studying OR10A2, a member of the olfactory receptor family involved in detecting odors. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the OR10A2 protein, this antibody enables the accurate detection and analysis of OR10A2 expression in various cell types, making it a valuable tool for studies in sensory biology and olfactory research.OR10A2 is a specialized receptor that plays a crucial role in the olfactory system, contributing to our ability to detect and distinguish different odors.
Research on OR10A2 is important for understanding the molecular mechanisms underlying smell perception and could have implications for areas such as aromatherapy, food industry, and fragrance development. By studying OR10A2 expression and function, researchers can gain insights into how the olfactory system processes sensory information, leading to potential advancements in various fields related to sensory perception.
Antibody Name:
OR10A2 Antibody (PACO64355)
Antibody SKU:
PACO64355
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC, IF
Recommended Dilutions:
IHC:1:200-1:500, IF:1:100-1:500
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Olfactory receptor 10A2 protein (247-262AA)
IHC image of PACO64355 diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Immunofluorescence staining of Hela cells with PACO64355 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of PACO64355 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]