The OPN3 Polyclonal Antibody (CAB15803) is a valuable tool for researchers studying OPN3, a key protein involved in the visual system and circadian rhythm regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the OPN3 protein, researchers can accurately detect and analyze its expression in various cells and tissues.OPN3, also known as encephalopsin, is a member of the opsin family of proteins and is primarily expressed in the retina, skin, and brain. Its function in mediating light detection and regulating the body's response to light plays a crucial role in visual processes and circadian rhythm synchronization.
Research on OPN3 is essential for understanding its role in vision, photoreception, and biological rhythms, making it a promising target for studies in vision science, neuroscience, and chronobiology.By using the OPN3 Polyclonal Antibody (CAB15803), researchers can uncover important insights into the mechanisms underlying OPN3's function and its implications in various physiological processes. This antibody provides a reliable tool for investigating OPN3 in both normal and pathological conditions, paving the way for advancements in vision research and chronobiology.
Product Name:
OPN3 Rabbit Polyclonal Antibody
SKU:
CAB15803
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human OPN3 (NP_055137.2).
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein.
Purification Method:
Affinity purification
Gene ID:
23596
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using OPN3 Rabbit pAb (CAB15803) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
