UniProt Protein Function: | OPN1SW: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Defects in OPN1SW are the cause of tritan color blindness (CBT). Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 7q32.1Cellular Component: integral to plasma membraneMolecular Function: G-protein coupled receptor activity; photoreceptor activity; receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; phototransduction, visible light; visual perception; phototransduction; retinoid metabolic process; signal transduction; protein-chromophore linkageDisease: Tritanopia |
UniProt Protein Details: | |
NCBI Summary: | This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. [provided by RefSeq, Jul 2008] |
UniProt Code: | P03999 |
NCBI GenInfo Identifier: | 4502387 |
NCBI Gene ID: | 611 |
NCBI Accession: | NP_001699.1 |
UniProt Secondary Accession: | P03999,Q13877 |
UniProt Related Accession: | P03999 |
Molecular Weight: | 39,135 Da |
NCBI Full Name: | short-wave-sensitive opsin 1 |
NCBI Synonym Full Names: | opsin 1 (cone pigments), short-wave-sensitive |
NCBI Official Symbol: | OPN1SWÂ Â |
NCBI Official Synonym Symbols: | BCP; BOP; CBTÂ Â |
NCBI Protein Information: | short-wave-sensitive opsin 1; blue-sensitive opsin; blue cone photoreceptor pigment |
UniProt Protein Name: | Short-wave-sensitive opsin 1 |
UniProt Synonym Protein Names: | Blue cone photoreceptor pigment; Blue-sensitive opsin; BOP |
Protein Family: | Probable aspartic-type endopeptidase |
UniProt Gene Name: | OPN1SWÂ Â |
UniProt Entry Name: | OPSB_HUMAN |