OPCML Rabbit Polyclonal Antibody (CAB2778)
- SKU:
- CAB2778
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | OPCML Rabbit Polyclonal Antibody |
SKU: | CAB2778 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-345 of human OPCML (NP_002536.1). |
Sequence: | ASAV PMAE FQWF KEET RLAT GLDG MRIE NKGR MSTL TFFN VSEK DYGN YTCV ATNK LGNT NASI TLYG PGAV IDGV NSAS RALA CLWL SGTL LAHF FIKF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | OPCM; OBCAM; IGLON1; OPCML |
Positive Sample: | U-87MG,293T,HeLa,Mouse brain,Mouse pancreas,Mouse kidney,Rat brain,Rat pancreas,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 38kDa |
Observed MW: | 38kDa |
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 4978 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |