The OPCML Polyclonal Antibody (CAB2778) is a valuable tool for researchers studying OPCML, a cell adhesion molecule involved in various cellular processes, including cell signaling and adhesion. This antibody, produced in rabbits, is known for its high specificity and sensitivity towards OPCML in human samples, making it suitable for Western blot analysis.OPCML, also known as Opioid Binding Protein/Cell Adhesion Molecule (OPCML), plays a crucial role in cell-cell interactions and is implicated in tumorigenesis and metastasis in various cancers. Its expression levels have been shown to be dysregulated in cancer cells, making it a potential biomarker for disease progression and prognosis.
The OPCML Polyclonal Antibody enables the detection and analysis of OPCML protein levels in different cell types, providing insights into its function and potential therapeutic targets in cancer research.By understanding the role of OPCML in cancer development and progression, researchers can develop targeted therapies that aim to manipulate OPCML expression and function for personalized treatment strategies. The OPCML Polyclonal Antibody is a valuable resource for researchers looking to explore the intricate mechanisms of OPCML in cancer biology and other disease contexts.
Product Name:
OPCML Rabbit Polyclonal Antibody
SKU:
CAB2778
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 246-345 of human OPCML (NP_002536.1).
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
4978
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using OPCML antibody (CAB2778) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
