The OneCut1 Polyclonal Antibody (CAB12774) is a valuable tool for researchers studying OneCut1, a transcription factor involved in developmental processes, particularly in the nervous system. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting OneCut1 protein in human samples, making it ideal for use in Western blot applications.OneCut1, also known as Hnf6, plays a key role in the regulation of gene expression during embryonic development, particularly in the formation of neuronal circuits.
Its involvement in neuronal differentiation and axonal growth makes it a focal point of research in neurobiology and neurodevelopmental disorders. By targeting OneCut1 with this antibody, researchers can further elucidate its functions and mechanisms in order to advance our understanding of neural development and potentially identify therapeutic targets for neurological conditions.
Product Name:
ONECUT1 Rabbit Polyclonal Antibody
SKU:
CAB12774
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 167-292 of human ONECUT1 (NP_004489.1).
This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3175
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ONECUT1 antibody (CAB12774) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
