Oncostatin M Rabbit Monoclonal Antibody (CAB8705)
- SKU:
- CAB8705
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Developmental Biology
Description
Product Name: | Oncostatin M Rabbit Monoclonal Antibody |
SKU: | CAB8705 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Oncostatin M (P13725). |
Sequence: | MGVL LTQR TLLS LVLA LLFP SMAS MAAI GSCS KEYR VLLG QLQK QTDL MQDT SRLL DPYI RIQG LDVP KLRE HCRE RPGA FPSE ETLR GLGR RGFL QTLN |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | OSM; oncostatin-M; Oncostatin M |
Positive Sample: | HepG2,Jurkat,Mouse liver,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 28kDa |
Observed MW: | 21kDa |
This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 5008 |
Clone Number: | ARC1194 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |