The Oncostatin M Rabbit Monoclonal Antibody (CAB8705) is a valuable tool for researchers studying Oncostatin M (OSM), a cytokine involved in diverse biological processes such as cell differentiation, proliferation, and immune response modulation. This antibody, produced using rabbit monoclonal technology, offers high specificity and sensitivity for detecting OSM in human samples.Validated for use in Western blotting, immunohistochemistry, and immunofluorescence applications, this antibody binds specifically to OSM, allowing for precise detection and quantification in various cell types and tissues.
Its versatility makes it an ideal choice for studies in immunology, oncology, and inflammatory diseases.Oncostatin M has been implicated in the pathogenesis of various diseases, including cancer, inflammation, and autoimmune disorders. By targeting OSM and understanding its role in these conditions, researchers can potentially develop novel therapeutic strategies for treating these illnesses. The Oncostatin M Rabbit Monoclonal Antibody (CAB8705) is a valuable tool for advancing our knowledge of OSM biology and its implications in human health and disease.
Product Name:
Oncostatin M Rabbit Monoclonal Antibody
SKU:
CAB8705
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Oncostatin M (P13725).
This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
5008
Clone Number:
ARC1194
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Oncostatin M Rabbit mAb (CAB8705) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
