Oncostatin M Rabbit Polyclonal Antibody (CAB6163)
- SKU:
- CAB6163
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
Product Name: | Oncostatin M Rabbit Polyclonal Antibody |
SKU: | CAB6163 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-252 of human Oncostatin M (NP_065391.1). |
Sequence: | AAIG SCSK EYRV LLGQ LQKQ TDLM QDTS RLLD PYIR IQGL DVPK LREH CRER PGAF PSEE TLRG LGRR GFLQ TLNA TLGC VLHR LADL EQRL PKAQ DLER SGLN IEDL EKLQ MARP NILG LRNN IYCM AQLL DNSD TAEP TKAG RGAS QPPT PTPA SDAF QRKL EGCR FLHG YHRF MHSV GRVF SKWG ESPN RSRR HSPH QALR KGVR RTRP SRKG KRLM TRGQ LPR |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | OSM; Oncostatin M |
Positive Sample: | HepG2,NIH/3T3,Mouse uterus,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 28kDa |
Observed MW: | 28kDa |
This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 5008 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |