null

Omentin Monoclonal Antibody [PAT6C11AT] (CPAB0076)

SKU:
CPAB0076
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT6C11AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

Omentin Monoclonal Antibody [PAT6C11AT] (CPAB0076)

The Omentin Antibody (CPAB0076) is a polyclonal antibody designed for research involving Omentin, a protein associated with metabolic diseases and inflammation. This antibody, raised in rabbits, has high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry. It specifically binds to the Omentin protein, allowing for precise detection and analysis in different cell types.Omentin, also known as intelectin-1, is a novel adipokine with anti-inflammatory and insulin-sensitizing properties. It has been linked to obesity, type 2 diabetes, and cardiovascular diseases, making it a promising target for research in metabolic disorders.

Understanding the role of Omentin in these conditions is crucial for developing potential therapeutic interventions that target metabolic pathways and inflammation.Overall, the Omentin Antibody (CPAB0076) is a valuable tool for researchers in the fields of metabolism, endocrinology, and inflammation, providing insights into the role of Omentin in health and disease. It is ideal for studies investigating the mechanisms underlying metabolic disorders and exploring potential treatment options for related conditions.

Product Name:Omentin Antibody
Product Sku:CPAB0076
Size:5μg
Host Species:Mouse
Immunogen:Anti-human Omentin mAb, clone PAT6C11AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Omentin protein 17-313 amino acids purified from Ecoli.
Clone:PAT6C11AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:Omentin antibody was purified by protein-A affinity chromatography.
Isotype:IgG1
Background:Omentin is a recently recognized gene highly localized to the mental tissue (visceral adipose tissue). Omentin is present in the stromal vascular cells in the adipose tissue rather than in the adipocytes. Omentin is predominantly expressed in the visceral adipose tissue than the subcutaneous tissue, with the omentin mRNA being 150 times higher in the visceral adipose tissue. Omentin has also been detected in human blood using western blot analysis, and seems to increase insulin-stimulated glucose uptake in 3T3-L1 adipocytes in mice. Omentin seems to increase Akt phosphorylation irrespective of insulin presence. Its role in glucose metabolism and obesity remains to be described; an insulin-sensitizing action is possible.Differences in Omentin expression has been noted in adipose tissue from normals and patients with inflammatory bowel disease although its significance is unknown
Synonyms:Intelectin-1, HL1, LFR, HL-1, INTL, ITLN, hIntL.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products