The OMA1 Polyclonal Antibody (CAB14437) is a valuable tool for researchers studying OMA1, an important protein involved in mitochondrial dynamics and quality control. This antibody is produced in rabbits and is highly specific for human samples, making it an ideal choice for Western blot applications. By binding to the OMA1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it particularly useful for studies in the fields of cell biology, biochemistry, and mitochondrial dysfunction.OMA1 is a protease that plays a critical role in maintaining mitochondrial health and function by regulating processes such as mitochondrial fusion and fission, protein turnover, and oxidative stress response.
Dysregulation of OMA1 activity has been linked to various mitochondrial disorders, neurodegenerative diseases, and aging-related conditions. By investigating the function and regulation of OMA1, researchers can gain valuable insights into the underlying mechanisms of these disorders and potentially identify new therapeutic targets for intervention.Overall, the OMA1 Polyclonal Antibody (CAB14437) offers researchers a reliable tool for studying the role of OMA1 in mitochondrial biology and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of mitochondrial dynamics and quality control mechanisms in health and disease.
Product Name:
OMA1 Rabbit Polyclonal Antibody
SKU:
CAB14437
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 360-524 of human OMA1 (NP_660286.1).
Enables metalloendopeptidase activity. Involved in several processes, including HRI-mediated signaling; proteolysis; and regulation of mitochondrion organization. Located in mitochondrial inner membrane.
Purification Method:
Affinity purification
Gene ID:
115209
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using OMA1 Rabbit pAb (CAB14437) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
