The Olig2 Rabbit Monoclonal Antibody (CAB4555) is a valuable tool for researchers studying Olig2, a transcription factor essential for the development of oligodendrocytes in the central nervous system. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications such as immunohistochemistry and flow cytometry.Olig2 is known for its role in regulating the differentiation of oligodendrocyte precursor cells, as well as its involvement in brain tumor formation.
By targeting Olig2, researchers can better understand the mechanisms underlying oligodendrocyte development and the pathogenesis of brain tumors such as gliomas.With its high specificity and sensitivity, the Olig2 Rabbit Monoclonal Antibody is an essential tool for studies focusing on neural development, neurodegenerative diseases, and brain cancer research. Its ability to detect Olig2 in cell samples enables detailed analyses that contribute to the advancements in these fields of study.
Product Name:
Olig2 Rabbit Monoclonal Antibody
SKU:
CAB4555
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Olig2 (Q13516).
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
Purification Method:
Affinity purification
Gene ID:
10215
Clone Number:
ARC1032
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Olig2 Rabbit mAb (CAB4555) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
