The Olig1 Polyclonal Antibody (CAB17251) is a valuable tool for researchers studying Olig1, a transcription factor important for oligodendrocyte development and myelination in the central nervous system. This rabbit polyclonal antibody is highly specific and reacts strongly with human samples, making it ideal for use in Western blot applications to detect and analyze Olig1 protein levels in various cell types.Olig1 is a critical regulator of oligodendrocyte differentiation and myelination, processes that are essential for proper nerve function in the central nervous system. Dysregulation of Olig1 expression has been implicated in neurological disorders such as multiple sclerosis and leukodystrophies, making it an important target for research in neurobiology and neurodegenerative diseases.
By utilizing the Olig1 Polyclonal Antibody, researchers can gain valuable insights into the role of Olig1 in oligodendrocyte development and function, with potential implications for the development of novel therapeutic strategies for neurological disorders involving demyelination. This antibody is an essential tool for investigating the molecular mechanisms underlying oligodendrocyte biology and myelination processes in the central nervous system.
Product Name:
Olig1 Rabbit Polyclonal Antibody
SKU:
CAB17251
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-271 of human Olig1 (NP_620450.2).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neuron fate commitment. Predicted to be part of chromatin. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
116448
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Olig1 Rabbit pAb (CAB17251) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
