The OGFR Polyclonal Antibody (CAB7074) is a valuable tool for researchers studying the opioid growth factor receptor (OGFR), a cell surface receptor involved in the regulation of cell growth and proliferation. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various applications including Western blot and immunohistochemistry.OGFR, also known as the zeta opioid receptor, plays a key role in the regulation of cell proliferation, differentiation, and apoptosis. Its involvement in these processes makes it a promising target for research in areas such as cancer biology, neurobiology, and pharmacology.
By detecting and analyzing the expression of OGFR in different cell types, researchers can gain insights into its function and potential therapeutic implications in various diseases.The OGFR Polyclonal Antibody (CAB7074) enables precise and reliable detection of the OGFR protein, making it an essential tool for studies focusing on the molecular mechanisms underlying cell growth and survival. Its high specificity and sensitivity make it ideal for use in immunological and cancer research, providing valuable insights into the role of OGFR in health and disease.
Product Name:
OGFR Rabbit Polyclonal Antibody
SKU:
CAB7074
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2).
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported.
Purification Method:
Affinity purification
Gene ID:
11054
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB7074) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
