OGDH Rabbit Polyclonal Antibody (CAB6391)
- SKU:
- CAB6391
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | OGDH Rabbit Polyclonal Antibody |
SKU: | CAB6391 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human OGDH (NP_001003941.1). |
Sequence: | DPLG ILDA DLDS SVPA DIIS STDK LGFY GLDE SDLD KVFH LPTT TFIG GQES ALPL REII RRLE MAYC QHIG VEFM FIND LEQC QWIR QKFE TPGI MQFT NEEK RTLL ARLV RSTR FEEF LQRK WSSE KRFG LEGC EVLI PALK TIID KSSE NGVD YVIM GMPH RGRL NVLA NVIR KELE QIFC QFDS KLEA ADEG SGDV KYHL GMYH RRIN RVTD RNIT LSLV ANPS HLEA ADPV VMGK TKAE QFYC GDTE GKKV RPRE RRAR QIVK APCS SMEF RSPT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:10 - 1:100 |
Synonyms: | E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1; OGDH |
Positive Sample: | LNCaP,Mouse brain,Rat heart,Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 116kDa |
Observed MW: | 110kDa |
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4967 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |