OGDH Monoclonal Antibody (CAB22163)
- SKU:
- CAB22163
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | OGDH Monoclonal Antibody |
SKU: | CAB22163 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 869-1023 of human OGDH (NP_002532.2). |
Sequence: | RSSF DEML PGTH FQRV IPED GPAA QNPE NVKR LLFC TGKV YYDL TRER KARD MVGQ VAIT RIEQ LSPF PFDL LLKE VQKY PNAE LAWC QEEH KNQG YYDY VKPR LRTT ISRA KPVW YAGR DPAA APAT GNKK THLT ELQR LLDT AFDL DVFK NFS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50-1:200 |
Synonyms: | E1k; E1o; KGD1; OGDC; AKGDH; OGDH2; OGDHD; OGDH-E1; OGDH |
Positive Sample: | HeLa,MCF7,Mouse heart,Mouse skeletal muscle,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Nucleus |
Calculated MW: | 116kDa |
Observed MW: | 116kDa |
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4967 |
Clone Number: | ARC55379 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |