The ODR4 Antibody (PAC059117) is a highly specific and sensitive tool for studying ODR4, a protein involved in a variety of cellular processes. This polyclonal antibody is produced in rabbits and has been validated for use in Western blot applications, allowing for accurate detection of ODR4 in human samples.ODR4 is known for its role in mediating cellular responses to various stimuli, including stress and environmental changes. Research suggests that ODR4 may play a critical role in regulating cell growth, differentiation, and survival, making it a promising target for further investigation in the fields of cell biology and cancer research.
By using the ODR4 Antibody, researchers can gain valuable insights into the functions and interactions of ODR4 in different cell types, paving the way for a better understanding of its potential implications in disease development and treatment. Whether studying signal transduction pathways or unraveling the molecular mechanisms underlying cellular responses, this antibody is an essential tool for advancing scientific knowledge in the field of molecular biology.
Western Blot. Positive WB detected in: NIH/3T3 whole cell lysate. All lanes: ODR4 antibody at 4.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52, 49, 38, 48 kDa. Observed band size: 52 kDa.
Immunofluorescence staining of HepG2 cells with PACO59117 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of PACO59117 diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
May play a role in the trafficking of a subset of G-protein coupled receptors.
Synonyms:
Protein odr-4 homolog (hODR-4) (LAG1-interacting protein) (Transactivated by transforming growth factor β protein 1), ODR4, C1orf27 TTG1 TTG1A
UniProt Protein Function:
May play a role in the trafficking of a subset of G-protein coupled receptors.
