ODF2 Rabbit Polyclonal Antibody (CAB15630)
- SKU:
- CAB15630
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
Product Name: | ODF2 Rabbit Polyclonal Antibody |
SKU: | CAB15630 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 630-829 of human ODF2 (NP_702911.1). |
Sequence: | IISD LRSR IEHQ GDKL EMAR EKHQ ASQK ENKQ LSLK VDEL ERKL EATS AQNI EFLQ VIAK REEA IHQS QLRL EEKT RECG TLAR QLES AIED ARRQ VEQT KEHA LSKE RAAQ NKIL DLET QLSR TKTE LSQL RRSR DDAD RRYQ SRLQ DLKD RLEQ SEST NRSM QNYV QFLK SSYA NVFG DGPY STFL TSSP IRSR SPPA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CT134; ODF84; ODF2/1; ODF2/2; ODF2 |
Positive Sample: | HepG2,Jurkat,293T,Mouse brain,Mouse lung,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | centriolar subdistal appendage, centriole, centrosome, ciliary basal body, ciliary transition fiber, cilium, cytosol, nucleus, sperm flagellum, spindle pole |
Calculated MW: | 95kDa |
Observed MW: | 80kDa |
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. This gene encodes one of the major outer dense fiber proteins. Alternative splicing results in multiple transcript variants. The longer transcripts, also known as 'Cenexins', encode proteins with a C-terminal extension that are differentially targeted to somatic centrioles and thought to be crucial for the formation of microtubule organizing centers.
Purification Method: | Affinity purification |
Gene ID: | 4957 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |