The ODF1 Polyclonal Antibody (CAB16023) is a valuable tool for researchers studying ODF1, a protein involved in sperm tail formation and function. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting. By specifically binding to ODF1, this antibody enables the detection and analysis of ODF1 in a variety of cell types, making it an ideal choice for investigations in reproductive biology and fertility research.
ODF1, also known as outer dense fiber protein 1, plays a crucial role in the structural integrity and motility of sperm tails, making it a key player in male fertility. Dysregulation of ODF1 has been linked to various reproductive disorders, making it a potential target for therapeutic interventions in infertility. By studying ODF1 and its functions, researchers can gain valuable insights into male reproductive health and potentially develop new treatments for fertility-related conditions.
Product Name:
ODF1 Rabbit Polyclonal Antibody
SKU:
CAB16023
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human ODF1 (NP_077721.2).
The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein.
Purification Method:
Affinity purification
Gene ID:
4956
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ODF1 Rabbit pAb (CAB16023) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
