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OCT2 Transcription Factor Activity Assay

SKU:
TFAB00150
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
OCT2
Reactivity:
Human
Mouse
Rat
€599
Frequently bought together:

Description

system_update_altDatasheet

OCT2 Transcription Factor Activity Assay

Based on the information provided in the URL, here is a product description:The OCT2 Transcription Factor Activity Assay is a cutting-edge research tool designed for the precise measurement of OCT2 transcription factor activity in biological samples. This assay kit offers unparalleled sensitivity and specificity, allowing for accurate and reproducible results across a wide range of experimental conditions.OCT2 is a key transcription factor with a crucial role in regulating gene expression and cellular function. Its activity is known to impact various biological processes, including cell proliferation, differentiation, and immune responses.

By measuring OCT2 activity, researchers can gain valuable insights into the molecular mechanisms underlying these processes and potentially identify novel therapeutic targets.Whether investigating the role of OCT2 in cancer progression, immune system function, or developmental biology, the OCT2 Transcription Factor Activity Assay provides researchers with a powerful tool to advance their understanding of this essential transcription factor. With its user-friendly protocol and reliable performance, this assay kit is a valuable addition to any laboratory conducting research in the field of molecular biology and gene regulation.

Product Name:OCT2 Transcription Factor Activity Assay
Product Code:TFAB00150
Target:OCT2
Synonyms:Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2
Reactivity:Human, Mouse, Rat
Sample Types:Nuclear or cell lysates

The Assay Genie Oct2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: cytoplasm; nucleus

Molecular Function:protein domain specific binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response

NCBI Summary:The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
UniProt Code:P09086
NCBI GenInfo Identifier:123402
NCBI Gene ID:5452
NCBI Accession:P09086.3
UniProt Secondary Accession:P09086,Q16648, Q7M4M8, Q9BRS4,
UniProt Related Accession:P09086
Molecular Weight:400
NCBI Full Name:POU domain, class 2, transcription factor 2
NCBI Synonym Full Names:POU class 2 homeobox 2
NCBI Official Symbol:POU2F2  
NCBI Official Synonym Symbols:OCT2; OTF2; Oct-2  
NCBI Protein Information:POU domain, class 2, transcription factor 2; OTF-2; homeobox protein; octamer-binding protein 2; octamer-binding transcription factor 2; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2
UniProt Protein Name:POU domain, class 2, transcription factor 2
UniProt Synonym Protein Names:Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2
Protein Family:POU domain, class 2, transcription factor
UniProt Gene Name:POU2F2  
UniProt Entry Name:PO2F2_HUMAN
AntibodiesELISA Kits
POU2F2 Antibody (PACO01197)Human OCT2 (Octamer-binding protein 2) ELISA Kit (HUES02126)
POU2F2 Antibody (PACO11379)
POU2F2 Antibody (PACO14800)
POU2F2 Antibody (PACO14801)
POU2F2 Antibody (PACO23687)

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