Occludin Rabbit Polyclonal Antibody (CAB2601)
- SKU:
- CAB2601
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Occludin Rabbit Polyclonal Antibody |
SKU: | CAB2601 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-522 of human Occludin (NP_002529.1). |
Sequence: | TDYT TGGE SCDE LEED WIRE YPPI TSDQ QRQL YKRN FDTG LQEY KSLQ SELD EINK ELSR LDKE LDDY REES EEYM AAAD EYNR LKQV KGSA DYKS KKNH CKQL KSKL SHIK KMVG DYDR QKT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | BLCPMG; PTORCH1; PPP1R115; Occludin |
Positive Sample: | Mouse lung,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Membrane, Multi-pass membrane protein, tight junction. |
Calculated MW: | 59kDa |
Observed MW: | 65kDa/ |
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Purification Method: | Affinity purification |
Gene ID: | 100506658 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |