The OCC1 Polyclonal Antibody (PAC020136) is a valuable tool for researchers studying OCC1, a protein involved in immune regulation and inhibition of immune responses. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the OCC1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and cancer research.OCC1, also known as an immune inhibitory receptor, plays a key role in maintaining immune homeostasis by regulating inflammation and suppressing allergic reactions.
Its functional significance in immune response modulation makes it a promising target for research in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the mechanisms of OCC1 activity is essential for developing innovative therapies that manipulate immune function in these disease contexts.
Antibody Name:
OCC1 Antibody (PACO20136)
Antibody SKU:
PACO20136
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human C12orf75
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20136(C12orf75 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20136(C12orf75 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
C12orf75 (chromosome 12 open reading frame 75), also known as AGD3 or OCC1, is a protein that in humans is encoded by the C12orf75 gene. C12orf75 is high expression in placenta, skeletal muscle, kidney and pancreas tissues.
