OBSCN Rabbit Polyclonal Antibody (CAB18110)
- SKU:
- CAB18110
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | OBSCN Rabbit Polyclonal Antibody |
SKU: | CAB18110 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1621-1710 of human OBSCN (NP_443075.3). |
Sequence: | EPKV VFAK EQPA HREV QAEA GASA TLSC EVAQ AQTE VTWY KDGK KLSS SSKV RVEA VGCT RRLV VQQA GQAE AGEY SCEA GGQQ LSFR LQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | UNC89; RHABDO1; ARHGEF30; OBSCN |
Cellular Localization: | cytosol, M band, myofibril, nuclear body, plasma membrane, sarcolemma, Z disc |
Calculated MW: | 868kDa |
Observed MW: | Refer to figures |
The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 84033 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |