The OASL Polyclonal Antibody (PACO07450) is a valuable tool for researchers studying the OASL protein, an essential component of the innate immune response against viral infections. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the OASL protein, allowing for precise detection and analysis in a variety of cell types.OASL, a member of the OAS family of proteins, plays a crucial role in antiviral defense mechanisms by mediating the activation of immune response pathways.
Its involvement in immune signaling makes it a key target for investigation in virology and infectious disease research. Understanding the function of OASL is vital for developing strategies to enhance antiviral immunity and combat viral infections effectively.Overall, the OASL Polyclonal Antibody is a reliable tool for scientists seeking to explore the role of OASL in immune response regulation and antiviral defense mechanisms. Its specificity and sensitivity make it an excellent choice for studies in immunology, virology, and other related fields.
Antibody Name:
OASL Antibody (PACO07450)
Antibody SKU:
PACO07450
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000-1:20000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from human OASL. at AA range: 1-50
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of HELA cells using primary antibody diluted at 1:2000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour).
Synonyms:
2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)
UniProt Protein Function:
OASL: a protein of the 2'-5'-oligoadenylate synthetase family, but does not have 2'-5'-OAS activity. Binds double-stranded RNA and DNA. Interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Contains a ubiquitin-like domain that interacts with methyl CpG-binding protein 1.
