The OAS3 Polyclonal Antibody (CAB9481) is a valuable tool for researchers studying OAS3, a protein involved in the innate immune response against viral infections. This antibody, raised in rabbits, is highly specific to OAS3 and has been validated for use in various applications, including Western blotting. By targeting OAS3, researchers can better understand the mechanisms by which this protein helps to defend against viral invaders, making it a key player in antiviral defense pathways.
OAS3 is known for its ability to detect and respond to viral RNA, triggering the activation of enzymes that degrade viral genetic material and inhibit viral replication. By studying OAS3, researchers can gain insight into how the immune system combats viral infections and potentially uncover new targets for antiviral therapies. The OAS3 Polyclonal Antibody is an essential tool for any lab looking to delve deeper into the complex world of antiviral immunity.
Product Name:
OAS3 Rabbit Polyclonal Antibody
SKU:
CAB9481
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-620 of human OAS3 (NP_006178.2).
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
Purification Method:
Affinity purification
Gene ID:
4940
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using OAS3 Rabbit pAb (CAB9481) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
