The OAS1 Polyclonal Antibody (CAB2530) is a valuable tool for researchers studying OAS1, a protein involved in the innate immune response to viral infections. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for use in experiments such as Western blotting.OAS1 is a key player in the antiviral response, producing molecules that inhibit viral replication and spread within the body. By targeting OAS1 with this antibody, researchers can better understand the mechanisms behind viral infections and potentially develop new strategies for combating them.
This antibody binds specifically to the OAS1 protein, allowing for accurate detection and analysis in a variety of cell types. Its versatility and reliability make it a valuable tool for research in virology, immunology, and infectious diseases.Overall, the OAS1 Polyclonal Antibody (CAB2530) offers researchers a powerful tool for investigating the role of OAS1 in the immune response to viral infections, with potential implications for the development of new antiviral therapies.
Product Name:
OAS1 Rabbit Polyclonal Antibody
SKU:
CAB2530
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human OAS1 (NP_058132.2).
This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12.
Purification Method:
Affinity purification
Gene ID:
4938
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using OAS1 Rabbit pAb (CAB2530) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
