OAS1 Rabbit Polyclonal Antibody (CAB2530)
- SKU:
- CAB2530
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | OAS1 Rabbit Polyclonal Antibody |
SKU: | CAB2530 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human OAS1 (NP_058132.2). |
Sequence: | MMDL RNTP AKSL DKFI EDYL LPDT CFRM QINH AIDI ICGF LKER CFRG SSYP VCVS KVVK GGSS GKGT TLRG RSDA DLVV FLSP LTTF QDQL NRRG EFIQ EIRR QLEA CQRE RAFS VKFE VQAP RWGN PRAL SFVL SSLQ LGEG VEFD VLPA FDAL GQLT GGYK PNPQ IYVK LIEE CTDL QKEG EFST CFTE LQRD FLKQ RPTK LKSL IRLV KHWY QNCK KKLG KLPP QYAL ELLT VYAW ERGS MKTH FNTA QGFR TVLE LVIN YQQL CIYW TKYY DFKN PIIE KYLR RQLT KPRP VILD PADP TGNL GGGD PKGW RQLA QEAE AWLN YPCF KNWD GSPV SSWI LLVR PPAS SLPF IPAP LHEA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | OIAS; IFI-4; OIASI; IMD100; E18/E16; OAS1 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum, Microsome, Mitochondrion, Nucleus, Secreted. |
Calculated MW: | 46kDa |
Observed MW: | 40kDa |
This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12.
Purification Method: | Affinity purification |
Gene ID: | 4938 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |