NYX Rabbit Polyclonal Antibody (CAB7830)
- SKU:
- CAB7830
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | NYX Rabbit Polyclonal Antibody |
SKU: | CAB7830 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1). |
Sequence: | LLYL DRNS IAFV EEGA FQNL SGLL ALHL NGNR LTVL AWVA FQPG FFLG RLFL FRNP WCCD CRLE WLRD WMEG SGRV TDVP CASP GSVA GLDL SQVT FGRS SDGL CVDP EELN LTTS SPGP SPEP AATT VSRF SSLL SKLL APRV PVEE AANT TGGL ANAS LSDS LSSR GVGG AGRQ PWFL LASC LLPS VAQH VVFG LQMD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | CLRP; NBM1; CSNB1; CSNB4; CSNB1A; NYX |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
Purification Method: | Affinity purification |
Gene ID: | 60506 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |