The NXPH3 Antibody (PAC022461) is a polyclonal antibody designed for research involving NXPH3, a cell surface molecule known to be involved in synaptic transmission and neuronal signaling. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.NXPH3 is a member of the Neurexophilin family, which plays a critical role in modulating synaptic transmission by interacting with neurexins on the presynaptic membrane. Research has suggested that NXPH3 may be involved in regulating neurotransmitter release and synaptic plasticity, making it a key target for studies in neuroscience and neurobiology.
Furthermore, understanding the function of NXPH3 in the brain may provide insights into neurological disorders such as autism, schizophrenia, and epilepsy, where abnormalities in synaptic transmission and neuronal signaling have been implicated. By using the NXPH3 Antibody, researchers can investigate the role of NXPH3 in these conditions and potentially uncover new therapeutic targets for treating these disorders.
Antibody Name:
NXPH3 Antibody (PACO22461)
Antibody SKU:
PACO22461
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human NXPH3.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HT-29 cells, using NXPH3 antibody.
Background:
May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins By similarity.
Synonyms:
Neurexophilin-3; KIAA1159; NPH; UNQ687/PRO1327;
UniProt Protein Function:
NXPH3: May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins. Belongs to the neurexophilin family.Protein type: Secreted, signal peptide; Secreted; HormoneChromosomal Location of Human Ortholog: 17q21.33Cellular Component: extracellular regionMolecular Function: receptor bindingBiological Process: neuropeptide signaling pathway
