NXF5 Antibody (PACO28686)
- SKU:
- PACO28686
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | NXF5 Antibody (PACO28686) |
| Antibody SKU: | PACO28686 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Nuclear RNA export factor 5 protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: NXF5 antibody at 4µg/ml + HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 46, 43, 20, 36, 35 kDa Observed band size: 46 kDa . |
 | Immunofluorescent analysis of HepG2 cells using PACO28686 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO28686 at dilution of 1:100. |
| Background: | Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons. |
| Synonyms: | Nuclear RNA export factor 5 (TAP-like protein 1) (TAPL-1), NXF5, TAPL1 |
| UniProt Protein Function: | NXF5: Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons. A chromosomal aberration involving NXF5 has been observed in one patient with a syndromic form of mental retardation and short stature. Pericentric inversion inv(X)(p21.1;q22) that interrupts NXF5. Belongs to the NXF family. 6 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: Xq22Cellular Component: cytoplasm; nucleusMolecular Function: protein binding; RNA bindingBiological Process: mRNA export from nucleus; multicellular organismal development; poly(A)+ mRNA export from nucleus; RNA transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is one member of a family of nuclear RNA export factor genes. The encoded protein can bind RNA, and is implicated in mRNA nuclear export. However, this protein has lost several C-terminal protein domains found in other family members that are required for export activity, and may be an evolving pseudogene. Alternatively spliced transcript variants have been described, but most are candidates for nonsense-mediated decay (NMD) and may not express proteins in vivo. [provided by RefSeq, Jul 2009] |
| UniProt Code: | Q9H1B4 |
| NCBI GenInfo Identifier: | 20978537 |
| NCBI Gene ID: | 55998 |
| NCBI Accession: | Q9H1B4.1 |
| UniProt Secondary Accession: | Q9H1B4,Q9H1B0, Q9H1B1, Q9H1B2, Q9H1B3, A2RRM0, B1AV82 B1AV83, B1AV84, B1AV85 |
| UniProt Related Accession: | Q9H1B4 |
| Molecular Weight: | 42,162 Da |
| NCBI Full Name: | Nuclear RNA export factor 5 |
| NCBI Synonym Full Names: | nuclear RNA export factor 5 |
| NCBI Official Symbol: | NXF5Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | nuclear RNA export factor 5 |
| UniProt Protein Name: | Nuclear RNA export factor 5 |
| UniProt Synonym Protein Names: | TAP-like protein 1; TAPL-1 |
| Protein Family: | Nuclear RNA export factor |
| UniProt Gene Name: | NXF5Â Â |
| UniProt Entry Name: | NXF5_HUMAN |