The NXF2 Polyclonal Antibody (PAC010983) is a valuable tool for researchers studying NXF2, a nuclear RNA export factor involved in the transport of mRNA from the nucleus to the cytoplasm. This antibody, raised in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By binding to the NXF2 protein, this antibody enables accurate detection and analysis of NXF2 expression in a variety of cell types, making it an ideal choice for studies in molecular biology and RNA transport research.
NXF2 plays a crucial role in the regulation of gene expression by facilitating the export of mRNA molecules from the nucleus, a process essential for protein synthesis in eukaryotic cells. Dysregulation of NXF2 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising therapeutic target for drug development. Understanding the function of NXF2 is essential for uncovering its role in human health and disease, paving the way for potential treatments targeting RNA export mechanisms.
NXF2: Involved in the export of mRNA from the nucleus to the cytoplasm. Belongs to the NXF family.Protein type: RNA-bindingChromosomal Location of Human Ortholog: Xq22.1Cellular Component: nuclear RNA export factor complex; cytoplasm; nucleusMolecular Function: RNA binding; nucleotide bindingBiological Process: mRNA export from nucleus; multicellular organismal development; RNA transport
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of nuclear RNA export proteins. The encoded protein is associated with the nuclear envelope and aids in the export of mRNAs. There is a closely related paralog of this gene located adjacent on chromosome X and on the opposite strand. [provided by RefSeq, Aug 2013]
