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NUR77 Polyclonal Antibody (CAB23940)

SKU:
CAB23940
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
$155 - $431
Frequently bought together:

Description

NUR77 Polyclonal Antibody (CAB23940)

The Nur77 Polyclonal Antibody (CAB23940) is a vital tool for researchers studying Nur77, a nuclear receptor involved in immune regulation and cell differentiation. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in various applications, including Western blotting.Nur77, also known as NR4A1, is a key player in the immune system, regulating apoptosis, inflammation, and metabolism. Its expression has been linked to various diseases, including cancer, autoimmune disorders, and metabolic conditions.

By targeting Nur77, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially develop new therapeutic strategies.This polyclonal antibody enables the detection and analysis of Nur77 in different cell types, making it an essential tool for studies in immunology, cancer biology, and metabolic research. With its high reactivity and specificity, the Nur77 Polyclonal Antibody is a valuable asset for scientists aiming to unravel the complexities of immune regulation and disease pathogenesis.

Product Name:NUR77 Polyclonal Antibody
Product Code:CAB23940
Reactivity:Human, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:500-1:1000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:293T-Nr4a1-His-C

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific DNA binding activity. Involved in cellular response to corticotropin-releasing hormone stimulus; fat cell differentiation; and negative regulation of cell cycle. Acts upstream of or within several processes, including positive regulation of transcription by RNA polymerase II; regulation of apoptotic process; and skeletal muscle cell differentiation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including bone; genitourinary system; hemolymphoid system; nervous system; and submandibular gland primordium. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1).

Immunogen:Recombinant protein of mouse NUR77.
Sequence:Email for sequence
Synonyms:Hmr, N10, TR3, Gfrp, Hbr1, NP10, TIS1, GFRP1, Hbr-1, NGFIB, nur77, NGFI-B, NUR77-1, NUR77-2
Calculated MW:65kDa
Observed MW:67kDa

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