NUP85 Rabbit Polyclonal Antibody (CAB11629)
- SKU:
- CAB11629
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | NUP85 Rabbit Polyclonal Antibody |
SKU: | CAB11629 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 427-656 of human NUP85 (NP_079120.1). |
Sequence: | CPEL GRVS LELH IERI PLNT EQKA LKVL RICE QRQM TEQV RSIC KILA MKAV RNNR LGSA LSWS IRAK DAAF ATLV SDRF LRDY CERG CFSD LDLI DNLG PAMM LSDR LTFL GKYR EFHR MYGE KRFA DAAS LLLS LMTS RIAP RSFW MTLL TDAL PLLE QKQV IFSA EQTY ELMR CLED LTSR RPVH GESD TEQL QDDD IETT KVEM LRLS LARN LARA IIRE GSLE GS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Nup75; FROUNT; NPHS17; NUP85 |
Positive Sample: | HT-29,U-87MG,A-549,LO2,HeLa,Mouse brain,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, Nucleus membrane, centromere, cytoskeleton, kinetochore, nuclear pore complex, spindle. |
Calculated MW: | 75kDa |
Observed MW: | 70kDa |
This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 79902 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |