The NUP62 Polyclonal Antibody (CAB2499) is a valuable tool for researchers studying the nuclear pore complex protein NUP62. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blotting.NUP62 is a key component of the nuclear pore complex, which regulates the transport of molecules in and out of the cell nucleus. Dysregulation of NUP62 has been linked to various diseases, including cancer and neurodegenerative disorders.
By targeting NUP62 with this antibody, researchers can study its expression and localization in different cell types, providing insight into its role in cellular function and disease pathology.With its high reactivity and specificity, the NUP62 Polyclonal Antibody is an essential tool for those investigating the molecular mechanisms of nuclear pore complex function and its implications in human health and disease.
Product Name:
NUP62 Rabbit Polyclonal Antibody
SKU:
CAB2499
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 403-522 of human NUP62 (NP_036478.2).
Cytoplasm, Nucleus, cytoskeleton, nuclear pore complex, spindle pole.
Calculated MW:
53kDa
Observed MW:
62kDa
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.
Purification Method:
Affinity purification
Gene ID:
23636
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NUP62 Rabbit pAb (CAB2499) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
